CAT POO COULD BE THE KEY TO CURING THESE DEBILITATING DISEASES
Source: Huffpost (Extract)
Posted: August 04, 2024
A new study suggests that toxins found in cat feces might hold potential for treating Alzheimer’s and other neurological disorders, such as Parkinson’s Disease.
In this research, scientists utilized an engineered form of Toxoplasma gondii, a common parasite found in cat feces, to deliver proteins directly to the brains of mice.
As reported by The Independent: “Historically, neurological healthcare has struggled with the challenge of delivering targeted treatments across the blood-brain barrier and into specific neurons.”
Interestingly, Toxoplasma gondii is carried in a dormant state by about one-third of the global population and has evolved to move from the digestive system to the brain, where it can secrete proteins into neurons.
What does this mean for our brains?
Many neurological disorders are associated with protein dysfunction, making this groundbreaking research a potential game-changer in addressing these issues in ways not previously possible.
The study, a collaboration between Tel Aviv University and the University of Glasgow, involved creating an artificial parasite to test its ability to deliver proteins directly into affected brain cells.
Researchers focused on engineering the parasites to deliver the MeCP2 protein, which is considered a promising therapeutic target for Rett syndrome—a severe neurological disorder caused by mutations in the MECP2 gene.
Fortunately, the parasite successfully produced and delivered the protein to the intended cell locations, offering a hopeful future for treating neurological disorders.
However, researchers urge us to not get too excited yet
Professor Lilach Sheiner, a leading author of the study from the University of Glasgow’s School of Infection and Immunity, noted: “While the concept is promising, it does come with challenges, particularly regarding the risks associated with Toxoplasma infection.
“For our work to become a viable treatment, it will require many more years of careful research and development to enhance its effectiveness and ensure safety.”
We’re eager to see where this research leads.